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rabbit anti alox5  (Proteintech)


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    Proteintech rabbit anti alox5
    Rabbit Anti Alox5, supplied by Proteintech, used in various techniques. Bioz Stars score: 95/100, based on 56 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/rabbit+anti+alox5/5+Lipoxygenase+Antibody/pm39222758-70-16-14
    Average 95 stars, based on 56 article reviews
    rabbit anti alox5 - by Bioz Stars, 2026-09
    95/100 stars

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    other:

    Article Title: Ethyl acetate fraction of Thesium chinense Turcz. alleviates chronic obstructive pulmonary disease through inhibition of ferroptosis mediated by activating Nrf2/SLC7A11/GPX4 axis.
    Article Snippet: Ethnopharmacological relevance: Thesium chinense Turcz., a traditional Chinese herbal medicine, displays good therapeutic efficiency against respiratory diseases (e.g. pneumonia, pharyngitis) in clinical applications, however, its effects on COPD and the mechanism of action are still unclear.. Aim of the study: This study aims to investigate the therapeutic effect of the ethyl acetate fraction of Thesium chinense Turcz. (TCEA) on COPD and reveal the underlying mechanism.. Materials and methods: A cigarette smoke (CS)-induced mouse COPD model was established, and the efficacy of TCEA was evaluated using peripheral blood testing, HE and Masson staining, qRT-PCR and ELISA assays.



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    MGST1 was up-regulated, but ALOX5 was down-regulated in DDP-resistant NSCLC samples and cells

    Journal: Iranian Journal of Basic Medical Sciences

    Article Title: Microsomal glutathione transferase 1 confers cisplatin resistance of non-small cell lung cancer via interaction with arachidonate lipoxygenase 5 to repress ferroptosis

    doi: 10.22038/ijbms.2024.79203.17160

    Figure Lengend Snippet: MGST1 was up-regulated, but ALOX5 was down-regulated in DDP-resistant NSCLC samples and cells

    Article Snippet: The membranes were blocked with 5% skim milk for one hour and then incubated with primary antibodies against MGST1 (PA5-79670, 1:1000, Thermo Fisher), ALOX5 (#3289, 1:1000, CST, USA), glutathione peroxidase4 ( GPX4, A21440, 1:500, ABclonal, Wuhan, China), solute carrier family 7 member 11 (SLC7A11, A2413, 1:500, ABclonal), Acyl-CoA synthetase (ACSL4, A20414, 1:1000, ABclonal), and reduced glyceraldehyde-phosphate dehydrogenase (GAPDH, A19056, 1:10000, ABclonal) overnight at 4 ° C, followed by incubation with horseradish peroxidase-conjugated secondary antibody (AS014, 1:2000, ABclonal) for one hour.

    Techniques:

    MGST1 led to ferroptosis inhibition in NSCLC cells via direct interaction with ALOX5

    Journal: Iranian Journal of Basic Medical Sciences

    Article Title: Microsomal glutathione transferase 1 confers cisplatin resistance of non-small cell lung cancer via interaction with arachidonate lipoxygenase 5 to repress ferroptosis

    doi: 10.22038/ijbms.2024.79203.17160

    Figure Lengend Snippet: MGST1 led to ferroptosis inhibition in NSCLC cells via direct interaction with ALOX5

    Article Snippet: The membranes were blocked with 5% skim milk for one hour and then incubated with primary antibodies against MGST1 (PA5-79670, 1:1000, Thermo Fisher), ALOX5 (#3289, 1:1000, CST, USA), glutathione peroxidase4 ( GPX4, A21440, 1:500, ABclonal, Wuhan, China), solute carrier family 7 member 11 (SLC7A11, A2413, 1:500, ABclonal), Acyl-CoA synthetase (ACSL4, A20414, 1:1000, ABclonal), and reduced glyceraldehyde-phosphate dehydrogenase (GAPDH, A19056, 1:10000, ABclonal) overnight at 4 ° C, followed by incubation with horseradish peroxidase-conjugated secondary antibody (AS014, 1:2000, ABclonal) for one hour.

    Techniques: Inhibition